Neuromuscular blocking agents and intubation

Tracheal intubation without neuromuscular blocking agents

tracheal intubation without the use of neuromuscular blocking agents

Tracheal Intubation Without the Use of Neuromuscular Blocking Agents

I read with keen interest the article by Imani et al. (1) in which the authors compare tracheal intubating conditions following intravenous (IV) administration of remifentanil 5 μg/kg or alfentanil 50 μg/kg followed by induction of anesthesia with propofol 2 mg/kg in 100 adult patients premedicated with IV midazolam 1 mg. Intubating conditions were assessed (scoring 1 to 4) by ease of laryngosc...

endotracheal intubation without neuromuscular blocking agents: is it a good and safe option?

Neuromuscular Blocking Agents

• Neuromuscular blocking agents are used to improve conditions for tracheal intubation, to provide immobility during surgery, and to facilitate mechanical ventilation. • The main site of action of neuromuscular blocking agents (muscle relaxants) is on the nicotinic cholinergic receptor at the endplate of muscle. They also have effects at presynaptic receptors located on the nerve terminal. • Su...